Maria Casagrande-Santiago is Bobby and Ronnie Anne's mother.
She is a tall woman with dark skin, black hair tied up in a tight bun, and two pairs of eyelashes.
She has only been seen wearing a nurse uniform which consists of a white scrub, a white cap with a red cross, and black short heeled shoes.
- In "Changing the Baby", it's revealed that Lori apparently gave Maria a brooch that used to belong to Great Grandma Harriet.
- In "Shell Shock", it is revealed that she is a nurse.
- Her high heels look similar to Ms. DiMartino's.
- Both Aleksandra Radwan (Polish) and Talya Barkai (Hebrew), also voiced Lily and Leon.
- Maria constantly wears her nurse uniform, even when she isn't at work.
- Though she has occasionally been seen without her hat.
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