Not much is known about her, except that she runs a daycare center that the Loud parents want Lily to get into.
She is a round woman, with brown hair, black glasses, white pearl earrings, and red lipstick. She wears a yellow dress, with a white frilled collar, white lines at the end of the sleeves, and black shoes with heels.
According to Lisa, Dr. Shuttleworth has a slight astigmatism, just by examining her eyeglasses.
It is possible she was named after the Shuttleworth Collection, a collection of older aircraft and automobiles in the UK.